Raman bIO-Optics

  • Measuring principle

    Raman spectroscopy

  • Sampling probe compatibility

    Raman Rxn-10 probe

  • Sample interface

    Temperature: –30 to 150 °C / -22 to 302 °F

  • Pressure

    Max pressure: 13.8 barg / 200 psig

  • Wetted materials

    Body: 316L stainless steel
    Window: Proprietary material, optimized for bioprocesses
    Process connection: PG13.5
    Surface finish: Ra 15 with electropolish
    Adhesive: USP Class VI and ISO 10993 compatible

  • Length

    120, 220, 320, or 420 mm
    4.73, 8.67, 12.60, 16.54 inch

  • Diameter

    12 mm / 0.48 inch

  • Sterilization method

    Autoclave

  • Process connection

    PG13.5

Field of application
Raman bIO-Optics are versatile immersion optics used in conjunction with the Rxn-10 probehead and compatible with standard bioreactor ports. The fixed focus design provides long-term measurement stability along with superior signal performance, essential for transferable, high performance Raman-based bioprocess analysis. Available in industry standard lengths, Raman bIO-Optics are ideally suited for both glass and plastic benchtop bioreactor/fermenter applications requiring headplate entry.

Cell culture: glucose, lactate, glutamine, amino acids, cell density, titerFermentation: glycerol, methanol, ethanol, sorbitol, biomassDownstream: aggregation, protein crystallization, formula stability, product CQA, protein concentration, buffer excipients

Benefits
Immersion optics for multi-component bioprocess measurementCompatible with standard bioreactor portsFixed-focus designAvailable in 12 mm diameter with Pg 13.5 threaded connector120, 220, 320, or 420 mm lengthsAutoclavable

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